groups |
Biochemical parameter |
Control |
200 mg/kg |
800 mg/kg |
Before |
After |
Before |
After |
Before |
After |
Diabetic |
urea |
53.62 ± 4.77 |
55.24 ± -10.84 |
52.25 ± 2.8 |
45.25 ± 7.2 |
53.57 ± 3.7 |
45.35 ± 7.57 |
Before – After |
-1.62 ± 15.61 |
7 ± -4.4 |
8.22 ± -3.87 |
Normal |
urea |
37 ± 2.78 |
37.6 ± 5.68 |
40.75 ± 4.06 |
33.87 ± 5.96 |
40.4 ± 15.8 |
32.3 ± 7.19 |
Before – After |
-0.6 ± -2.9 |
6.88 ± -1.9* |
8.1 ± 8.61* |
Diabetic |
Uric acid |
2.11 ± 0.08 |
2.05 ± 0.5 |
1.82 ± 0.05 |
2.02 ± 0.17 |
1.88 ± 0.27 |
2.2 ± 0.59 |
Before – After |
0.06 ± -0.42 |
-0.2 ± -0.12 |
-0.32 ± 0.09 |
Normal |
Uric acid |
1.7 ± 0.09 |
1.5 ± 0.15 |
2.07 ± 0.1 |
1.73 ± 0.26 |
1.65 ± 0.1 |
1.3 ± 0.3 |
Before – After |
0.2 ± -0.06 |
0.34 ± -0.16 |
0.35 ± -0.2 |
Diabetic |
AST |
266.6 ± 94.5 |
517.8 ± 345.9 |
269.6 ± 66.5 |
259.6 ± 134.7 |
267.3 ± 64.9 |
251.5 ± 135.2 |
Before – After |
-251.2 ± -251.4 |
10 ± -68.2* |
15.8 ± -70.3* |
Normal |
AST |
187.6 ± 5.2 |
188.9 ± 24.88 |
180.25 ± 52.9 |
181.15 ± 93.7 |
185.1 ± 29.25 |
185.8 ± 21.35 |
Before – After |
-1.3 ± -19.68 |
-0.9 ± -40.8 |
-0.7 ± 7.9 |
Diabetic |
ALT |
99.87 ± 94.5 |
171.99 ± 178.1 |
101.25 ± 62.01 |
148.96 ± 64.51 |
103.71 ± 6.64 |
116.71 ± -39.36 |
Before – After |
-72.12 ± -83.6 |
-47.71 ± -2.5 |
-13 ± 46 |
Normal |
ALT |
51.5 ± 7.5 |
52 ± 7.49 |
53.75 ± 6.31 |
49.45 ± 6.81 |
52.7 ± 5.6 |
47.6 ± 8.1 |
Before – After |
-0.5 ± 0.01 |
4.3 ± -0.5 |
5.1 ± -2.5 |
Diabetic |
ALP |
1197.25 ± 37.41 |
2042.75 ± 297.41 |
1201 ± 590 |
1758 ± 175 |
1694.7 ± 124.9 |
1238.7 ± 162.9 |
Before – After |
-845.5 ± -260 |
-557 ± 415 |
-456 ± 38* |
Normal |
ALP |
602.66 ± 118.15 |
601.66 ± 125.03 |
606.75 ± 53.27 |
577.38 ± 68.49 |
605.8 ± 128.31 |
534.3 ± 122.31 |
Before – After |
1 ± -6.88 |
29.37 ± -15.22* |
71.5 ± 6* |
Values are given as means ± SD of 10 rats.
* p < 0.05, compared with control group |