| Metabolicpathway |
Associted genes |
| Adipocyte funtion and lipid metabolism |
ABCG1, APOE, ADRB3, CYP19A1,FABP2, LEPR, LRP2, MTP, PPARG |
| Beta cell dysfunction of the pancreas |
CPN10, HNF4A, TCF1, SUR1,KIR6.2,SLCA2A, UCP2, IAPP, INS, GCK, SIRT1,ARNT, FOXO1, NNT |
| Cellcycleregulators |
HHEX1/IDE, CDKAL1, CDK2A/B, CDC123/CAMKLD,TSPAN8, THADA, PALGPS2 |
| Cytoesqueleton and extracelular matrix |
ADAMTS9, ARHGEF11, ELMO1, NXPH1 |
| Energetic Balance |
PGC1,SIRT1, UCP2 |
| Incretinsystem |
DPPIV, GLP1, GIP, KCNQ1,KCNJ11 |
| Inflamation |
ADIPOQ, HLA-G, IL-6, TNFA |
| Liverfuntion |
GYS1,GCGR, IGF1, IGFBP2, HNF1A |
| Mechanism of insulin in tissue |
ATXN2, ATXN3, ENPP1, FTO, INSR, IRS1, IRS2, PIK3,PP1R3A, RBP4 |
| Morphognsis of the pancreas |
FOXO1,FOXA2, JAZF1, NOTCH2, RORA,TCF7L2 |
| Proteosome |
UBQLNL |
| Trace elements and mineral metabolism |
SLC30A8 |
| Transporterstoaromaticaminoacids |
SLC16A11, SLC16A13 |
| Vascular and hypothalamic disfuntion |
ELMO1, HPSE, HPSG, ICF7L2, NOS3, NXPH1 |
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