| Compound |
MW (<500) |
LogP (<5) |
HBD (<5) |
HBA (<10) |
MR (40-130) |
Number of criteria met (At least 3) |
Freely rotatable bonds |
PSA |
MV |
| 3a |
408.4 |
3.2 |
1 |
8 |
110.0 |
All |
6 |
118.1 |
286.1 |
| 3b |
393.4 |
3.3 |
1 |
6 |
110.1 |
All |
6 |
81.6 |
302.5 |
| 3c |
397.8 |
5.7 |
1 |
5 |
108.9 |
All |
5 |
72.3 |
290.2 |
| 4a |
422.4 |
3.2 |
1 |
8 |
114.4 |
All |
6 |
118.1 |
301.3 |
| 4b |
407.4 |
3.3 |
1 |
6 |
114.5 |
All |
6 |
81.6 |
317.7 |
| 4c |
411.9 |
4.1 |
1 |
5 |
113.3 |
All |
5 |
72.3 |
305.3 |
| 5a |
453.4 |
3.8 |
1 |
11 |
115.6 |
4 |
7 |
164.0 |
291.4 |
| 5b |
438.4 |
3.9 |
1 |
9 |
115.8 |
All |
7 |
127.4 |
307.8 |
| 5c |
442.8 |
4.7 |
1 |
8 |
114.6 |
All |
6 |
118.1 |
295.4 |
| Indomethacin |
357.7 |
4.3 |
1 |
5 |
94.59 |
All |
4 |
68.5 |
269.5 |
|