Name Mode of Action References
Angiostatin K13 Inhibitor of endothelial cell growth and angiogenesis. [10]
DLαDifluoromethylornithine Inhibition of ornithine decarboxylase (ODC) and blocks angiogenesis [11]
Endostatin Inhibits endothelial cell proliferation; Potent inhibitor of angiogenesis and tumor growth as well. [12]
Fumagillin Inhibitor of endothelial cell proliferation and angiogenesis. [13]
Genistein Down regulates the transcription of genes involved in controlling angiogenesis. [14]
Minocycline Inhibits endothelial cell proliferation and angiogenesis. [15]
Staurosporine Blocks angiogenesis by inhibition of up regulated VEGF expression in tumor cells. [16]
(±)Thalidomide Inhibits biosynthesis of tumor necrosis factor α (TNFα); inhibits angiogenesis. [17]
Table 1: Angiogenesis inhibitors and their mode of action as anticancer agent.