| Name |
Mode of Action |
References |
| Actinomycin D |
Inhibits cell proliferation by forming complex with DNA and blocks production of mRNA (RNA polymerase inhibition); Induces apoptosis. |
[55] |
| Daunorubicin |
Complexes to DNA and blocks production of mRNA by RNA polymerase. |
[56] |
| Doxorubicin |
Inhibits reverse transcriptase and RNA polymerase by binding to DNA. |
[57] |
| Homoharringtonine |
Binds to the 80S ribosome in eukaryotic cells and inhibits protein synthesis by interfering with chain elongation. |
[58] |
| Idarubicin |
Antileukemia agent with higher DNA binding capacity and greater cytotoxicity than daunorubicin |
[59] |
