| Compound |
Cytotoxicity (%)a |
| RAW 264.7 |
VERO |
| 10 μM |
100 μM |
10 μM |
100 μM |
| 2 |
36.9 ± 2.6 |
43.6 ± 3.9 |
16.4 ± 1.2 |
46.5 ± 3.9 |
| 3 |
1.4 ± 0.1 |
24.2 ± 2.4 |
4.7 ± 0.3 |
19.0 ± 1.7 |
| 4 |
58.2 ± 4.4 |
95.1 ± 7.8 |
15.5 ± 1.4 |
35.9 ± 2.9 |
| 5 |
73.2 ± 5.9 |
90.9 ± 8.3 |
25.7 ± 2.4 |
91.8 ± 8.8 |
| Nifurtimox |
NA |
NA |
NA |
NA |
All the experiments were carried out in triplicate, and the data represent the mean
values (± S.D.)
NA inactive at concentration tested
aResults are reported as the percentage of non-viable VERO or RAW 264.7 cells
regarding the control. |
