Cell line |
IC50 (μM) |
Nifurtimox |
Compound 5 |
RAW 264.7 |
263.4 ± 25.4 |
6.1 ± 0.5 |
VERO |
>100 |
56.8 ± 5.4 |
The results are the means of two different experiments with a SD less than 10%
in all cases.
aIC50: concentration that produces 50 % of inhibitory effect. |