Table 2

Compound	Protein Synth. Inh.		Cytotoxicity (IC₅₀, nM)^b
Compound	(EC₅₀, nM)^a	A549	HCT116	Namalwa	A375
ANS	32	38.5	57.2	92	57.5
22	100	87.5	67	77.7	44.4

(a) Protein synthesis was evaluated using a DLD-1 4Ub-Luc colon cancer cell line.
(b) Cytotoxicity measurements, after 72 hours of drug treatment, performed with 4 tumor cell lines.

Table 2: Protein synthesis inhibition and cytotoxicity of ANS and compound 22.