Scheme 2:
Synthesis of 4-((4-methylpiperazin-1-yl) methyl)benzaldehyde (a
30-3
): (i) dibenzoyl peroxide, NBS, CCl
4
, reflux, 24 h; (ii) 4-methylpiperazine, CHCl3, 24 h; (iii) Raney Nickel alloy, formic acid 75%; reflux, 2 h.
