|
Comp |
Anti-inflammatory effect (%) |
Inhibition (%) |
|
100 µg/ml |
200 µg/ml |
100 µg/ml |
200 µg/ml |
IIa |
0.042 ± 0.00108 |
0.0487 ± 0.00039 |
55.78 |
48.73 |
IIb |
0.031 ± 0.00083 |
0.0423 ± 0.00080 |
66.63 |
55.47 |
IIc |
0.021 ± 0.00082 |
0.0321 ± 0.00193 |
77.15 |
66.21 |
IId |
0.033 ± 0.00086 |
0.0473 ± 0.00102 |
64.73 |
50.21 |
IIe |
0.028 ± 0.00100 |
0.0382 ± 0.00095 |
69.89 |
59.78 |
IIf |
0.025 ± 0.00097 |
0.0332 ± 0.00116 |
72.94 |
65.05 |
IIg |
0.048 ± 0.00047 |
0.0528 ± 0.00140 |
49.26 |
44.42 |
IIh |
0.017 ± 0.00396 |
0.0495 ± 0.00285 |
80 |
48.21 |
IIi |
0.049 ± 0.00030 |
0.0558 ± 0.00186 |
48.42 |
41.26 |
IIj |
0.023 ± 0.00045 |
0.0318 ± 0.00017 |
75.78 |
66.52 |
IIk |
0.036 ± 0.00023 |
0.0481 ± 0.00039 |
62.1 |
49.36 |
IIl |
0.037 ± 0.00029 |
0.0216 ± 0.00084 |
60.42 |
70.26 |
IIm |
0.029 ± 0.00037 |
0.0317 ± 0.00062 |
69.26 |
66.63 |
Ibuprofen |
0.018 ± 0.00039 |
0.0225 ± 0.00010 |
80.42 |
76.31 |
Control |
0.095 ± 0.00023 |
0.0950 ± 0.00023 |
---- |
---- |
|
The results are expressed as mean ± SDM (n=6). Significance was calculated by using one-way ANOVA with Dunnet’s t-test. |
Table 3: Anti-inflammatory activity by % inhibition of protein denaturation for derivatives (IIa-IIm). |