Potentiometric Titration of Paracetamol in glacial acetic acid with 0.1 N HCIO4 in glacial acetic acid, using platinum - calomel electrodes
Volume of 0.1 N HCIO4, ml Potential,Volts Volume of 0.1 N HCIO4,  ml Potential,Volts
5 0.49 15 0.525
5.5 0.49 16 0.525
6 0.49 17 0.53
7 0.49 18 0.53
8 0.495 19 0.53
9 0.5 20 0.535
10 0.5 21 0.535
11 0.504 22 0.535
12 0.514 23 0.535
13 0.514 24 0.535
14 0.525 25 0.535
Potentiometric Titration of Paracetamol in pyridine with 0.075 N soldiumethoxide in ethyl alcohol, using platinum – calomel electrodes
Volume of 0.075 N C2H5ONa, ml Potential, Volts Volume of 0.075 N C2H5ONa,  ml Potential, Volts
4 0.22 15 0.279
5 0.22 16 0.293
6 0.225 17 0.305
7 0.225 18 0.314
8 0.232 19 0.317
9 0.232 20 0.317
10 0.232 21 0.326
11 0.239 22 0.326
12 0.243 23 0.326
13 0.249 24 0.326
14 0.26 25 0.326
Potentiometric Titration of Paracetamol in dimethylformamide with 0.075 N sodium ethoxide in ethyl alcohol, using platinum-calomel electrodes.
Volume of 0.075 N C2H5ONa, ml Potential, Volts Volume of 0.075 N C2H5ONa,  ml Potential, Volts
2 0.22 17 0.262
3 0.224 18 0.273
4 0.227 19 0.28
5 0.227 20 0.282
6 0.227 21 0.285
7 0.227 22 0.288
8 0.227 23 0.291
9 0.227 24 0.291
10 0.223 25 0.291
11 0.223 26 0.291
12 0.223 27 0.291
13 0.226 28 0.291
14 0.231 29 0.291
15 0.235 30 0.291
16 0.247    
Potentiometric Titration of Paracetamol in Pyridine with 0.09 N sodium ethoxide in ethyl alcohol.
Volume of 0.09 N C2H5ONa, ml Potential, Volts Volume of 0.09 N C2H5ONa, ml Potential, Volts
3 0.385 15 0.415
4 0.385 16 0.415
5 0.385 17 0.42
6 0.385 18 0.42
7 0.385 19 0.42
8 0.395 20 0.42
9 0.395 21 0.42
10 0.395 22 0.42
11 0.4 23 0.42
12.1 0.405 24 0.42
13 0.415 25 0.42
14 0.415    
Potentiometric Titration of Paracetamol in dimethyl formamide with 0.09 N sodium ethoxide in ethylalcohol.
Volume of 0.09 N C2H5ONa, ml Potential, Volts Volume of 0.09 N C2H5ONa, ml Potential, Volts
0.5 0.395 13 0.415
1 0.395 14 0.42
2 0.395 15 0.42
3 0.395 16 0.42
4 0.395 17 0.42
5 0.395 18 0.42
6 0.395 19 0.42
7 0.395 20 0.42
8 0.4 21 0.42
9 0.4 22 0.42
10 0.4 23 0.42
11 0.405 24 0.42
12 0.405 25 0.42
pH-metric Titration of Paracetamol in ethyl alcohol with 0.083 N sodium ethoxide in ethylalcohol.
Volume of 0.083 N C2H5ONa, ml pH Volume of 0.083 N C2H5ONa, ml Potential, Volts
4 12 14.5 13.3
5 12.1 15 13.4
6 12.15 16 13.5
7 12.25 17 13.6
7.5 12.3 18 13.65
8 12.4 19 13.7
9 12.5 20 13.75
10 12.6 21 13.75
11 12.7 22 13.8
12 12.8 23 13.8
13 12.9 24 13.8
14 13.2 25 13.85
Table 1: The acid-base titrations of paracetamol in nonaqueous solvents.