| Case number |
Age |
Sex |
Postmortem interval |
Clinical diagnosis |
Pathology |
| BTRF002 |
80 |
M |
5 |
Parkinson’s disease
Deep brain stimulation |
Lewy body pathology - Limbic (transitional) pattern
* Infarct, recent/fresh, left parieto-occipital region
* Infarct, remote/cavitated, right caudate and putamen region
* Microinfarct, remote/cavitated, right anterior hippocampus
* Atherosclerosis and arteriolosclerosis
* Diffuse hypoxic/ischemic damage |
| BTRF003 |
73 |
M |
15 |
14 years history of Parkinson's disease
Gamma knife treatment of vestibular Schwannoma |
Diffuse neocortical pattern of Lewy body type pathology/
Diffuse Lewy body disease
* Early hypoxic/ischemic changes, mild
* Telangiectasia, right pons
* Metabolic gliosis
* Atherosclerosis, mild
* Arteriolosclerosis, moderate to severe |
| BTRF004 |
90 |
F |
19 |
Parkinson’s disease |
Limbic (transitional) pattern of Lewy body type pathology
Dementia with Lewy bodies clinical syndrome
* Hypoxic/ischemic changes
* Atherosclerosis/arteriolosclerosis |
| BTRF006 |
72 |
M |
11.5 |
Parkinson’s disease |
Diffuse neocortical type of Lewy body disease
* Encephalopathy, neurodegenerative, severe, consistent
with Lewy body disease diffuse neocortical type
* Metabolic gliosis, mild to moderate
* Atherosclerosis and arteriolosclerosis, mild
* Cerebral amyloid angiopathy (CAA), mild
* Leptomeningeal fibrosis, mild
* Enlarged pituitary gland (1.2 cm) |
| BTRF007 |
91 |
F |
20 |
Lewy body dementia |
Diffuse neocortical Lewy body pathology (Dementia with
Lewy bodies)
* Encephalopathy, neurodegenerative, severe to very severe,
alpha-synucleinopathy
* Cerebral amyloid angiopathy (CAA), moderate
* Athero- and arteriosclerosis, moderate
* Acute hypoxic ischemic change, moderate
* Metabolic gliosis, moderate
* Choroid plexus cyst |
| BTRF008 |
60 |
M |
19 |
Multiple system atrophy vsLewy body dementia |
Neocortical (diffuse) Lewy body disease, severe
* Encephalopathy, neurodegenerative with alpha-synucleinopathy
* Pons, 0.3 cm remote infarct
* Cerebellar infarcts, remote right x 2:1.0 x o.4 x 0.2 cm and
0.6 x 0.5 x 0.2 cm
* Occipital leukoencephalomalacia 1.0 x 0.7 x 0.3 cm
* Metabolic gliosis
* Arteriolosclerosis, mild |
|