Control   Mexico City   Comparison    
  Mean SD± Mean SD± p value % above the % above the control median
control mean
OZ  IgA 0.457 0.09 0.602 0.31 0.003 58.3 75
OZ  IgG 0.482 0.15 0.581 0.16 0.003 62.5 68.8
OZ  IgM 0.651 0.31 0.855 0.63 0.05 41.7 56.3
Actin IgA 0.596 0.19 0.679 0.26 0.08 54.2 62.5
Actin IgG 0.822 0.32 1.019 0.36 0.006 68.8 85.4
Actin IgM 0.724 0.22 0.873 0.35 0.016 68.8 68.8
TGM3 IgA 0.506 0.21 0.542 0.24 0.44 50 54.2
TGM3 IgG 0.659 0.22 0.825 0.3 0.002 68.8 70.8
TGM6 IgA 0.443 0.18 0.49 0.23 0.28 47.9 54.2
TGM6 IgG 0.589 0.17 0.736 0.37 0.016 58.3 66.7
GAD 65 IgA 0.406 0.14 0.452 0.17 0.15 50 66.7
GAD 65 IgG 0.578 0.17 0.671 0.2 0.019 66.7 72.9
GAD 65 IgM 0.58 0.18 0.674 0.28 0.05 62.5 62.5
CEREB IgA 0.511 0.17 0.617 0.34 0.06 41.7 54.2
CEREB IgG 0.545 0.23 0.845 0.44 0.0001 68.8 75
CEREB IgM 0.684 0.29 0.915 0.57 0.015 45.8 56.3
OZ=Occludin Zonulin, TGM3=Transglutaminase 3, TGM6=Transglutaminase 6, GAD-65=Glutamic Acid Decarboxylase, CEREB=Cerebellar peptide
Table 2. Serum autoantibodies in Controls v Mexico City Metropolitan Area children. Results are expressed in optical density units. Significant p-values are marked in bold. Percentages of the MCMA children that showed optical density values higher than the control mean and control median are also shown.
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