Symptoms |
Treatment without ascorbic acid |
Treatment with ascorbic acid |
1. Depressed Mood |
2 ± 0.16 |
0.54 ± 0.24* |
1.89 ± 0.20 |
1 ± 0.29* |
2. Feeling of guilt |
2.08 ± 0.24 |
0.38 ± 0.18* |
2.22 ± 0.22 |
1 ± 0.37* |
3. Suicide |
1.31 ± 0.35 |
0.31 ± 0.17* |
1.56 ± 0.38 |
0.67 ± 0.33 |
4. Insomnia-early |
1.23 ± 0.17 |
0.46 ± 0.18* |
1.33 ± 0.24 |
0.67 ± 0.24* |
5. Insomnia middle |
1 ± 0.23 |
0.15 ± 0.1* |
0.89 ± 0.26 |
0.11 ± 0.11* |
6. Insomnia-late |
0.77 ± 0.20 |
0 ± 0* |
0.89 ± 0.26 |
0.22 ± 0.15* |
7. Work &Activities |
2.46 ± 0.31 |
0.77 ± 0.32* |
1.89 ± 0.35 |
1 ± 0.33 |
8.Retardation |
0±0 |
0±0 |
0.22±0.22 |
0.11±0.11 |
9. Agitation |
1.08 ± 0.21 |
0.15 ± 0.1* |
1.44 ± 0.34 |
1 ± 0.29a |
10. Anxiety-psychic |
2.31 ± 0.17 |
0.69 ± 0.17* |
2 ± 0.29 |
1.56 ± 0.29a |
11. Anxiety-somatic |
1.77 ± 0.12 |
0.46 ± 0.14* |
1.67 ± 0.24 |
1.22 ± 0.22a |
12. Somatic-symptom GI |
0.92 ± 0.18 |
0.15 ± 0.10* |
0.89 ± 0.26 |
0.56 ± 0.24 |
13. Somatic-symptom |
1.15 ± 0.19 |
0.46 ± 0.14* |
1.33 ± 0.29 |
0.78 ± 0.28 |
14.Genital-symptoms |
1 ± 0.23 |
0.31 ± 0.17* |
0.89 ± 0.26 |
0.44 ± 0.24 |
15. Hypochondrias |
1.23 ± 0.38 |
0 ± 0* |
1.67 ± 0.37 |
0.78 ± 0.28a |
16. Weight loss (B) |
0.62 ± 0.24 |
0.62 ± .018 |
1.33 ± 0.29 |
0.33 ± 0.17* |
17. Insight |
0.08 ± 0.077 |
0 ± 0 |
0.22 ± 0.15 |
0.22 ± 0.15 |
Total score |
21.08 ± 1.26 |
5.46 ± 1.06* |
22.33 ± 1.9 |
11.56 ± 2.4*a |
*, significantly different from pretreatment at P ≤ 0.05; a, significantly different from group A at P ≤ 0.05; group A = ascorbic acid & antidepressant; group B = Placebo &
antidepressant
|