• Complaints seem out of proportion to organic pathology.
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• Treatment does not yield expected results despite an improved organic status.
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• New symptoms arise as old symptoms resolve.
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• The patient repeatedly raises issues/questions already addressed.
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• The patient seems to require more time and attention than usual.
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• The patient does not adhere to prescribed treatments.
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• The patient takes anxiolytic, sleep, or analgesic medication for a longer period of time than appropriate.
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• The patient resists the idea of attempting to wean from anxiolytic, sleep, or analgesic medications.
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• The patient exhibits a great deal of emotional distress.
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• The patient reports significant family problems in dealing with illness.
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• The patient overuses alcohol or other psychoactive substances.
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• Psychophysiological components could exacerbate the medical condition.
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