**p<0 01 difference between colchcine-administered groups vs vehicle
Figure 1: Response to colchicine intra-CA1 in saline conditioning task. Each animal was microinjected colchicine (1-8μg/ratl, intra-CA1) once. The animals after being recovered from surgery were assessed behaviorally by saline conditioning as detailed in experimental procedure. Control group avoided lesion-induced by colchicine but received saline (1 μl/rat, intra-CA1) and passed the same behavioral protocol.