Year of marketing Year of withdrawal Medication (s) Substance (s) Adverse drug reaction (s) GDR cases (N)
1966 1984 Enteroseptol Entero-Vioform Mexaform plus Clioquinol Dichlorquinol SMON* syndrome 0
1969 1984 Aminophenazone Oramon Pulmophyllin Aminophenazone Carcinogenic 0
< 1960 1984 Perclusone Wofapyrin henylbutazone combinations Bone marrow supression 11
1969 1984 Ketazon Kebuzon Bone marrow suppression 0
1981 1985 Sotropin H Somatrotopin Creutzfeld-Jacob Syndrome 0
1984 1985 Auroplex Lindane CNS reaction 5
1979 1985 Phenoro Canthaxanthin Retina sediments 3
< 1960 1986 Benedorm Pyrithyldion Dependence 1
< 1960 1986 Bromisoval (Alluval) Bromisovalerianyl Dependence 0
< 1960 1988 Phenylbutazone Phenylbutazone Bonemarrow suppression  84 (3 fatal)
*Sub-acute myelo-optico neuropathy
Table 2: Medications marketed in the German Democratic Republic (GDR) but withdrawn due to negative risk-benefit evaluations by health authorities, selected cases 1982 to 1990.