| Dosages
(mg/kg/d) |
Body weight
(g) |
Uterine wet weight |
Uterine blotted weight |
| Absolute (mg) |
Relative (mg/100g) |
Absolute (mg) |
Relative (mg/100g) |
| 0 |
66.2 |
± |
3.3 |
48.5 |
± |
3.4 |
73.3 |
± |
4.6 |
45.2 |
± |
3.2 |
68.4 |
± |
3.5 |
| 100 |
65.2 |
± |
2.7 |
58.7 |
± |
11.1 |
90.2 |
± |
18.4 |
54.5 |
± |
10.6 |
83.8 |
± |
17.3 |
| 300 |
66.2 |
± |
3.9 |
74.5 |
± |
14.9** |
112.6 |
± |
21.5** |
70.4 |
± |
13.6** |
106.4 |
± |
19.7** |
| 1,000 |
61.9 |
± |
2.4* |
170.3 |
± |
25.2** |
276.7 |
± |
50.7** |
129.6 |
± |
11.5** |
210.1 |
± |
24.7** |
| EE |
64.8 |
± |
2.4 |
176.2 |
± |
30.1 |
272.2 |
± |
46.9 |
141.0 |
± |
14.6 |
217.8 |
± |
21.9 |
| 100+EE |
64.4 |
± |
4.2 |
161.3 |
± |
36.5 |
252.4 |
± |
66.6 |
131.0 |
± |
13.3 |
203.9 |
± |
20.3 |
| 300+EE |
65.0 |
± |
2.5 |
144.6 |
± |
31.6 |
222.6 |
± |
49.6 |
112.6 |
± |
17.0# |
173.2 |
± |
26.0## |
| 1,000+EE |
62.3 |
± |
3.2 |
190.8 |
± |
40.4 |
305.9 |
± |
62.3 |
140.0 |
± |
19.8 |
224.6 |
± |
30.9 |
| TMX+EE |
63.2 |
± |
3.6 |
110.4 |
± |
11.8## |
174.5 |
± |
12.5## |
103.5 |
± |
10.4## |
163.6 |
± |
11.4## |
EE; ethinyl estradiol, TMX; tamoxifen.
* Significantly different from control at P<0.05.
** Significantly different from control at P<0.01.
# Significantly different from EE at P<0.05.
## Significantly different from EE at P<0.01. |
