biological parameters Light Grade 1 Moderate Grade 2 Severe Grade 3 Up to life-threatening Grade 4
Hematology
Hemoglobin N: H: 13-17 g/dl F: 11.5-16 g/dl 8.0-9.4 7.0-7.9 6.5-6.9 <6.5
Absolute neutrophil count N: 2000-7000 1.0-1.5 0.75-0.99 0.5-0.749 <0.5
Platelets N: 150 000 à 500 000mm3 75-99l 50-74.9 20-49.9l <20l
Biochemistry
Hypoglycemia N: <4.10 mmol/l 3.01-3.55 mmol/l 2.19-3.00 mmol/l 1.67-2.18 mmol/l <1.67 mmol/l
Hyperglycemia N: >5.90 mmol/l 6.44-8.90 mmol/l 8.91-13.88 mmol/l 13.89-27.76 mmol/l >27.76 mmol/l
Triglycerides N: 0.68-1.88 mmol - 4.52-8.47 mmol/l 8.48-13.55 mmol/l 8.48-13.55 mmol/l >13.55 mmol/l
Creatinine N: H: 62-115 µmol/l F: 53-97 µmol/l 120-180 180-360 360-720 >720
AST N: <40 µl/l 50-100 100-200 200-400 >400
ALT N: <45 µl/l 50-100 100-200 200-400 >400
Total bilirubin N: ≤ 20 µmol 18.7-25.5 27.2-42.5 44.2-85 >85
amylases: N: <90 µ/l 55-82.5 82.5-110 110-275 >275
N: Normal=normal value or normal interval ALT: Alanine aminotransférase ASAT: Aspartate Aminotransférase - Light grade or Grade 1: Symptoms which do not prevent, or which hardly prevent, the social and functional usual activities; - Moderate grade or Grade 2: Symptoms which prevent but not very much the social and functional usual activities - Severe grade or Grade 3: Symptoms which actually prevent the social and functional usual activities) - With a possibility to put at stake the prognosis or Grade 4: Symptoms which prevent from taking care of oneself or a necessity of medical or surgical intervention in order to prevent an
Table 2: Graduation biological manifestations of toxicity according to WHO 2010.