WHO stages of severity of some biological parameters  
biological parameters   No risk Light grade Moderate grade Severe grade Vital grade  p
amylase Placebo 2 (4.4%)   43 (95.6%)      0.767
(n=86) «Spiruline plus» 3 (77.5%)   38(12.5%)      
AST Placebo 41 (91.2%)   4(8.8%)     0.678
(n=86) «Spiruline plus» 39 (95.2%)   2 (4.8%)      
ALT Placebo 42 (93.4%)   3(6.6%)     1.000
(n=86) «Spiruline plus» 39 (95.2%)   2 (4.8%)      
total bilirubin Placebo 42 (100%)         NC
(n=80) «Spiruline plus» 38 (100%)          
glucose Placebo 38 (82.6%)   8 (17.4%)     0.363
(n=87) «Spiruline plus» 37 (90.2%)   4 (9.8%)      
hyperglycemia Placebo 44 (95%)   2(5.0%)     1.000
(n=87) «Spiruline plus» 39 (95.2%)   2 (4.8%)      
hypoglycemia Placebo 38 (82.6%)   8 (17.4%)     0.363
(n=87) «Spiruline plus» 37 (90.2%)   4 (9.8%)      
Triglycérides Placebo     44 (100%)     NC
(n=85) «Spiruline plus»     41(100%)      
Créatinine Placebo 44 (95.6%)   2(2.4%)     1.000
(n=87) «Spiruline plus» 40 (97.6%)   1 (2.4%)      
NC=not computable p=pFisher ALT: Alanine aminotransférase ASAT: Aspartate Aminotransférase - Light grade or Grade 1: Symptoms which do not prevent, or which hardly prevent, the social and functional usual activities - Moderate grade or Grade 2: Symptoms which prevent but not very much the social and functional usual activities - Severe grade or Grade 3: Symptoms which actually prevent the social and functional usual activities) - With a possibility to put at stake the prognosis or Grade 4: Symptoms which prevent from taking care of oneself or a necessity of medical or surgical intervention in order to prevent an organ from being affected for a long period of time, or a permanent handicap or death.
Table 6: Biochemical parameters according to WHO stages of severity in the placebo group and “Spiruline plus”.