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Figure 1: Wound closure of pM2b-treated lesions in the rat skin. Six round full-thickness wounds (6 mm diameter were made on each animal (n=8) and evaluated at different times after wounding. Three lesions at the right side were topically treated with pM2b (50 μl, 230 nM) and the other three lesions at the left side were treated with the vehicle saline. (A) Wound measurements as percentage of the initial wound area (0% closure). (B) Representative images of treated wounds. Mean ± SEM, n=24, bp<0.01, cp<0.05 vs control. |