Treatment Mean paw volume ± SEM Mean ankle joint diameter ± SEM
9 Day 18 Day 27 Day 36 Day 9 Day 18 Day 27 Day 36 Day
DC 9.42 ±0.5 9.74 ±0.3 9.23 ±0.3 9.73 ±0.2 11.06 ±0.08 11.85 ±0.4 10.55 ±0.3 10.55 ±0.3
STD 8.02 ±0.3 8.54 ±0.3 7.53 ±0.4* 6.93 ±0.2** 9.71 ±0.4 9.78 ±0.5* 8.34 ±0.3** 7.83 ±0.2**
SV (2 µg/ 200gm) 8.45 ±0.4 8.44 ±0.5 7.75 ±0.4* 6.92 ±0.4** 9.9 ±0.5 10.53 ±0.7 9.21 ±0.3* 8.76 ±0.3**
Values are expressed in mean ±SEM (n=6); *p<0.05, **p<0.01 vs. Disease control group, Data analysed by One-way ANOVA test followed by Dunnet’s multiple test for comparison. Treatment of various group are as follows, DC: Disease Control, STD: Indomethacin, SV: Scorpion venom.
Table 3: Effect of SV (2 μg/200 gm) on paw volumeand ankle joint diameter in CII induced arthritis.