Treatment Arthritic index score ± SEM Motility test score ± SEM Dorsal flexion Score ± SEM Stair climb ability Score ± SEM
9 DAY 18 DAY 27 DAY 36 DAY 9 DAY 18 DAY 27 DAY 36 DAY 9 DAY 18 DAY 27 DAY 36 DAY 9 DAY 18 DAY 27 DAY 36 DAY
DC   3.16 ± 0.3 3.16 ± 0.3 3.33 ± 0.2 2.83 ± 0.3 1.5 ± 0.2 2 ± 0 2 ± 0 1.33 ± 0.2 1.5 ± 0.08 1.46 ± 0.06 1.63 ± 0.06 1.63 ± 0.09 1.5 ± 0.4 0.66 ± 0.2 0.66 ± 0.3 0.83 ± 0.3
STD (P)   2.66 ± 0.3 2.5 ± 0.2 2.16 ± 0.1** 1.33 ± 0.2** 1.33 ± 0.2 1.33 ± 0.2* 1.16 ± 0.3* 0.5 ± 0.2* 1.36 ± 0.15 1.16 ± 0.09* 0.96 ± 0.06** 0.76 ± 0.12** 1.33 ± 0.4 1.5 ± 0.2* 2.16 ± 0.3** 2.16 ± 0.1**
SV (2 µg/200 gm) 2.33 ± 0.2 2.33 ± 0.2 2.16 ± 0.1** 1.33 ± 0.2** 1 ± 0.2 1.83 ± 0.1 1.16 ± 0.1* 0.5 ± 0.2* 1.16 ± 0.06 0.96 ± 0.09** 0.93 ± 0.11** 0.46 ± 0.08** 1 ± 0.4 1 ± 0.2 1.66 ± 0.2* 2.5 ± 0.2**
Values are expressed in mean ± SEM (n=6); *p<0.05, **p<0.01 vs. Disease control group, Data analysed by One-way ANOVA test followed by Dunnet’s multiple test for comparison. Treatment of various group are as follows, DC: Disease Control, STD: Indomethacin, SV: Scorpion venom, P: Preventive treatment, T: Therapeutic treatment.
Table 5: Effect of SV (2 μg/200gm) on Arthritic index and pain perception parameters in CII induced arthritis.