Figure 1: Liver histology. Panel A (H&E staining, 20x and 40x): Untreated at 3 h, 2.5 μM sorafenibat 3 h and 5.0 μM regorafenib at 3 h. Panel B (H&E staining, 20x): Untreated at 0 h, untreated at 3 h, 50 μM sorafenib at 3 h and 50 μM regorafenib at 3 h.