Stressor Name Mechanism Target
Adenosine Non-specific agonist of the Adenosine receptors Smooth muscle vasodilatation
Dipyridamole Increases extracellular concentration of adenosine by inhibiting reuptake Inhibition of the phosphodiesterase
Regadenason Specific agonist of the Adenosine A2a smooth muscle receptor Coronary smooth vessel vasodilatation
Dobutamine Strong β1 agonist, moderate β2 and mild α1 adrenergic receptors Increase oxygen demand, heart rate and blood pressure
Table 2: Pharmaceutical stressors to assess the coronary flow reserve (CFR).