Treatment Total No. of cells analysed per mice No. of cells with micronuclei % age of MN % Reduction P value
Group 1 Negative Control (Distilled water) 1000 2.35 ± 0.12      
Group 2 Positive control (EMS) 1000 7.23 ± 0.89     0.05*
Group 3 Ab- EAE 100 mg/kg bw 1000 2.32 ± 0.08      
Group 4 Ab- EAE 400 mg/kg bw 1020 2.30 ± 0.05      
Group 5 Ab- EAE 100 mg/kg + EMS 1000 7.09  ± 0.76 98 2  
Group 6 Ab-EAE 200 mg/kg + EMS 1000 6.88 ± 0.54 95.1 4.9 0.05*
Group 7 Ab-EAE 300 mg/kg + EMS 1000 6.05 ± 0.45 83.6 16.4 0.05*
Group 8 Ab-EAE 400 mg/kg + EMS 1000 5.74 ± 0.35 79.3 20.7 0.05*
Table 4: Effects of Ethyl Acetate Extract of Ajuga bracteosa on MNPCE frequencies (mean ± SD) in mice, induced with ethyl methane sulfonate (EMS) 117.5 mg/kg bw (1/4th LD50). Ab-EAE = Ethyl Acetate extract of Ajuga bracteosa