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Table 2: Bone mass and bone turnover biomarkers in placebo- and alcohol-treated rats supplemented with green tea polyphenols (GTP) in drinking water are shown. Results are expressed as mean values ± standard error of mean (SEM). All dietary treatment groups were analyzed by two-way analysis of variance (ANOVA) followed by Fisher’s protected least significant difference (Fisher’s LSD) post-hoc test to evaluate the effect of alcohol, GTP dose, or interaction. Within a row with different superscripts (x and y for alcohol effect; a and b for GTP; A, B and C for interaction) are significantly different by two-way ANOVA and Fisher’s LSD test (P<0.05). Within the Placebo groups (Placebo control, Placebo+0.1% GTP, and Placebo +0.5% GTP) or Alcohol groups (Alcohol control, Alcohol +0.1% GTP, Alcohol +0.5% GTP), data were analyzed by one-way ANOVA followed by Fisher’s LSD test to determine the effect of GTP levels (P<0.05). Abbreviations are: BMC, bone mineral content; BMD, bone mineral density; OC, osteocalcin; TRAP-5b, tartrate-resistant acid phosphatase-5b. |