Sample Dose No. of lines crossed
Control 10 ml/kg 130 ±  3.95
n- Hexane  50 mg/kg 126 ± 4.55
100 mg/kg 131 ± 4.25
CHCl3 50 mg/kg 119 ± 3.90
100 mg/kg 112 ± 3.65*
ETOAC 50 mg/kg 100 ± 3.85*
100 mg/kg 95 ± 4.10*
MeOH 50 mg/kg 105 ± 4.55
100 mg/kg 99.0 ± 2.98*
Bromazepam 5 mg/kg 9 ± 0.55***
Data represent the number of lines crossed by animal in box, 30 min after treatment with normal saline (10 ml/kg, control), SLO (50, 100 and 200 mg/kg) or bromazepam (5 mg/kg). Data presented as mean ± S.E.M, (n=6). *P<0.05, ***P<0.001, all compared with control.
Table 1: Effect of crude extract and fractions of Caralluma tuberculata in locomotive test (sedative activity)