Figure 3: Effect of pentosidine on collagen I/III gene expression in NIH3T3 fibroblasts.Gene expression of the α1 chain of collagen I(Col1a1) (A) and collagen III (Col3a1) (B) was decreased by pentosidine treatment. In the 0.5 and 1.0 μmol/L pentosidine groups, pentosidine significantly suppressed the gene expression of Col1a1 and Col3a1 compared with that in the control group. *po.<0.05; **p<0.01.