Author
Sample
Treatment
Exercise intervention
Primary end point
Birkeland et al.
20
5000 IU three times weekly
Cycle ergometry
Hct levels increased 19.0% (42.7 to 50.8%;P<0.001) and VO2max increased 7.5% (P=0.001)
Wilkerson et al.
15
150 IU/kg per week
Hb levels increased 7% (15.8 – 16.8 g/dl;P < 0.01) 12% in Hct (43- 49%; P < 0.01) 7% improvement in VO2max (P < 0.05) TTE was extended by 22% (P < 0.01)
Thomsen et al.
8
5000 IU injections (per protocol)
Hb increase by an average of 10.3 % (14.6-15.9 g/dl; P < 0.05) VO2max by 8.6% (P < 0.05). TTE was significantly increased by roughly 54.0% (P < 0.05)