Author

Sample

Treatment

Exercise intervention

Primary end point

Parisotto et al.

27

50 IU/kg three times weekly plus
intramuscular iron injections or
oral iron tablets

Treadmill or
cycle ergometer

(RhEPO + IM) and (RhEPO
+ PO) groups both
observed an increase in
Hb (6.9 +/- 0.6% and 12.0
+/- 0.7%, respectively)
and VO2 max (6.3+/- 1.8%
and 6.9 +/-1.1 %,
respectively)

Lundby et al.

8

5000 IU injections (per protocol)

Cycle ergometry

Hb and Hct increased
12% and 12%,
Respectively

Balsom et al.

6

2000 IU three times weekly

Treadmill

10.5% increase in Hb and
8% in VO2 max

RhEPO: Recombinant human erythropoietin
Hct: Hematocrit
Hb: Hemoglobin
IU: International Units
TTE: Time to exhaustion
Kg: Kilograms
IM: intramuscular
PO: oral
Table 2: Non-placebo RhEPO controlled studies [13, 20, 21].