Number

OR (95% CI)

P

DR (%)

FPR (%)

Maternal age (≥ 35 years)

302

 

 

 

 

Unaffected pregnancies

298

 

 

 

 

Trisomy 21

4

2.45 (0.57-8.13)

0.124

25.0

12.0

Increased fetal NT (≥ 2.4mm)

133

 

 

 

 

Unaffected pregnancies

121

 

 

 

 

Trisomy 21

12

58.6 (17.3-251)

<0.0001

75.0

4.9

Increased fetal NT (≥ 2.5mm)

126

 

 

 

 

Unaffected pregnancies

115

 

 

 

 

Trisomy 21

11

65.3 (20.2-243)

<0.0001

68.8

4.6

Increased fetal NT (≥ P 95)

92

 

 

 

 

Unaffected pregnancies

81

 

 

 

 

Trisomy 21

11

45.3 (14.2-168)

<0.0001

68.8

3.3

Posistive combined test

73

 

 

 

 

Unaffected pregnancies

59

 

 

 

 

Trisomy 21

14

285 (60.1-2639)

<0.0001

87.5

2.4

Table 2: Odd ratio (OR), detection rate (DR) and false positive rate (FPR) of maternal age, increased fetal NT in different cut-off point and positive combined test.
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