Increases Tracrolimus Levels Decreases Tacrolimus Levels Fluconazole, itraconazole, voriconazole, posaconazole, ketoconazole, clarithromycin, erythromycin, telithromycin, metronidazole, tinidazole, tigecycline, quinupristin/dalfopristin, basiliximab, nifedipine, diltiazem, felodipine, nicardipine, verapamil, clotrimazole, danazol, theophylline, metoclopramide, lansoprazole, dexlansoprazole, omeprazole, ethinyl estradiol, cimetidine, bromocriptine, methylprednisolone,    Sirolimus, phenytoin, fosphenytoin, phenobarbital, carbamazepine, rifampin, rifabutin, caspofungin, Echinacea, deferasirox,

Table 4: Drug Interactions between Tacrolimus and other Medications.