| Strategy |
Result |
Reference |
| Designated pathogen free breeding |
Defined microorganisms absent in the donor pigs |
[82-86] |
| Selection of pigs with low expression of PERV-A and PERV-B and absence of PERV-C in the genome |
Prevent PERV-A/C recombination, low expression, possibly no particle release |
[87,88] |
| RNA interference: Expression of PERV-specific siRNA |
Low expression, possibly no particle release |
[89-92] |
| Zinc finger nucleases (ZFN) |
Attempt to eliminate all PERV |
[93] |
| Vaccine |
Prevent transmission of PERV |
[94-98] |
| Antiretroviral drugs |
Prevention/therapy |
[99,100] |
