No. of patients |
Organ |
Genotyping Recipients
(R)/Donor (D) |
Outcome |
Reference |
158 |
Liver |
(R): CCR5-delta32 |
AR ↓ |
[31] |
|
|
(D): nd |
|
|
1227 |
Kidney |
(R): CCR5-delta32 |
Allograft Survival ↑ |
[16] |
(D): nd |
|
163 |
Kidney |
(R): CCR5-59029-A/G |
AR ↓ |
[42] |
(D): nd |
|
158 |
Heart |
(R): CCR5 No-E |
EAR ↓ |
[43] |
(D): nd |
|
266 |
Liver |
(R): 8 CCR5 SNPs |
Not significant ↑ |
[44] |
(D): nd |
|
384 |
Liver |
(R): CCR5-delta32 |
NAS 4foldé |
[45] |
(D): CCR5-delta32 |
Not significant |
173 |
Kidney |
(R): CCR5-delta32
CCR5-59029-A/G |
Not significant |
[46] |
(D): nd |
|
|
(nd= not done, AR= acute rejection, EAR= early acute rejection, NAS=
nonanastomotic biliary strictures) |
Table 1: Summary of studies focusing on the outcome of organ transplantation in
regard to different CCR5 polymorphism. In most cases, CCR5 genotyping was only
performed in recipients. |