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Figure 4: Serum anti-PCC and anti-MCC Ab levels produced by MHC haplo-identical BXSB mice immunized with PCC. Semi-allogeneic BXSB chimeric mice that received GFP/B6 × B10D2 F1 (H-2b/d) bone marrow were immunized with PCC. Serum anti-PCC and anti-MCC Ab levels between chimeric mice and the untreated BXSB mice were compared. Thick bars indicate mean value of Ab levels in chimeric mice group. Thin bars indicate mean value of Ab levels in untreated BXSB mice group. (A) ?: anti-PCC Ab levels in chimeric BXSB mouse serum (n=10). ?: anti-PCC Ab levels in nontreated BXSB mouse serum (n=10). *p<0.01 (B) ?: anti-MCC Ab levels in chimeric BXSB mouse serum (n=10). ?: anti-MCC Ab levels in BXSB mouse serum (n=10) **p<0.05. |