|
Entire group
(n=501) |
COPD
(n=133) |
Non-COPD
(n=388) |
P* |
Cough |
|
|
|
|
Trouble less |
470 (93.8) |
99 (87.6) |
371 (95.6) |
- |
Trouble much |
31 (6.2) |
14 (12.4) |
17 (4.4) |
0.002 |
Sputum |
|
|
|
|
Less frequent |
470 (93.8) |
100 (88.5) |
370 (95.4) |
- |
Much frequent |
31 (6.2) |
13 (11.5) |
18 (4.6) |
0.008 |
Trouble less |
470 (93.8) |
101 (89.4) |
369 (95.1) |
- |
Trouble much |
31 (6.2) |
12 (10.6) |
19 (4.9) |
0.026 |
Noise breathing |
|
|
|
|
Less frequent |
496 (99.0) |
111 (98.2) |
385 (99.2) |
- |
Much frequent |
5 (1.0) |
2 (1.8) |
3 (0.8) |
0.348 |
Dyspnoea |
|
|
|
|
Less frequent |
429 (85.8) |
76 (67.9) |
353 (91.0) |
- |
Much frequent |
71 (14.2) |
36 (32.1) |
35 (9.0) |
<0.001 |
Trouble less |
431 (86.2) |
77 (68.8) |
354 (91.2) |
- |
Trouble much |
69 (13.8) |
35 (31.3) |
34 (8.8) |
<0.001 |
MRC** Dyspnoae Scale |
|
|
|
|
Grade 0 |
44 (8.8) |
7 (6.2) |
37 (9.5) |
- |
Grade 1 |
248 (49.5) |
41 (36.3) |
207 (53.4) |
- |
Grade 2 |
148 (29.5) |
34 (30.1) |
114 (29.4) |
- |
Grade 3 |
54 (10.8) |
30 (26.5) |
24 (6.2) |
- |
Grade 4 |
7 (1.4) |
1 (0.9) |
6 (1.5) |
<0.001 |
NYHA€ Functional Class |
|
|
|
|
Class 1 |
136 (27.1) |
21 (18.6) |
115 (29.6) |
- |
Class 2 |
288 (57.5) |
55 (48.7) |
233 (60.1) |
- |
Class 3 |
70 (14.0) |
37 (32.7) |
33 (8.5) |
- |
Class 4 |
7 (1.4) |
0 (0.0) |
7 (1.8) |
<0.001 |
SGRQ¥ mean (SD) scores |
|
|
|
|
Symptoms score |
40 (20.0) |
46 (23.5) |
37 (16.5) |
0.009 |
Activity score |
50 (21.5) |
57 (21.7) |
47 (20.7) |
0.007 |
Impact score |
29 (24.9) |
40 (29.5) |
23 (18.5) |
<0.001 |
Total score |
37 (20.9) |
46 (24.0) |
32 (16.6) |
<0.001 |
Healthcare utilization in past 12 months£ |
|
|
|
|
Outpatient visits |
0.29 (1.18) |
0.82 (1.82) |
0.13 (0.86) |
<0.001 |
A & E visits |
0.27 (1.13) |
0.72 (1.68) |
0.14 (0.87) |
<0.001 |
Hospital admissions |
0.24 (1.02) |
0.62 (1.41) |
0.13 (0.85) |
<0.001 |
Values are numbers with percentages in parenthesis, unless otherwise stated.
*p between COPD and non-COPD subjects
** MRC= Medical Research Council
€ NYHA= New York Heart Association
¥ SGRQ= St George’s Respiratory Questionnaire (data only collected in 56 COPD
and 86 non-COPD subjects)
£ expressed in mean (SD) of unscheduled events not confined to cardiac causes
alone. |