Entire group (n=501) COPD (n=133)   Non-COPD (n=388) P*
Cough        
  Trouble less 470 (93.8) 99 (87.6) 371 (95.6) -
  Trouble much 31 (6.2) 14 (12.4) 17 (4.4) 0.002
Sputum        
  Less frequent 470 (93.8) 100 (88.5) 370 (95.4) -
  Much frequent 31 (6.2) 13 (11.5) 18 (4.6) 0.008
  Trouble less 470 (93.8) 101 (89.4) 369 (95.1) -
  Trouble much 31 (6.2) 12 (10.6) 19 (4.9) 0.026
Noise breathing        
  Less frequent 496 (99.0) 111 (98.2) 385 (99.2) -
  Much frequent 5 (1.0) 2 (1.8) 3 (0.8) 0.348
Dyspnoea        
  Less frequent 429 (85.8) 76 (67.9) 353 (91.0) -
  Much frequent 71 (14.2) 36 (32.1) 35 (9.0) <0.001
  Trouble less 431 (86.2) 77 (68.8) 354 (91.2) -
  Trouble much 69 (13.8) 35 (31.3) 34 (8.8) <0.001
MRC** Dyspnoae Scale        
  Grade 0 44 (8.8) 7 (6.2) 37 (9.5) -
  Grade 1 248 (49.5) 41 (36.3) 207 (53.4) -
  Grade 2 148 (29.5) 34 (30.1) 114 (29.4) -
  Grade 3 54 (10.8) 30 (26.5) 24 (6.2) -
  Grade 4 7 (1.4) 1 (0.9) 6 (1.5) <0.001
NYHA€ Functional Class        
  Class 1 136 (27.1) 21 (18.6) 115 (29.6) -
  Class 2 288 (57.5) 55 (48.7) 233 (60.1) -
  Class 3 70 (14.0) 37 (32.7) 33 (8.5) -
  Class 4 7 (1.4) 0 (0.0) 7 (1.8) <0.001
SGRQ¥ mean (SD) scores        
  Symptoms score 40 (20.0) 46 (23.5) 37 (16.5) 0.009
  Activity score 50 (21.5) 57 (21.7) 47 (20.7) 0.007
  Impact score 29 (24.9) 40 (29.5) 23 (18.5) <0.001
  Total score 37 (20.9) 46 (24.0) 32 (16.6) <0.001
Healthcare utilization in past 12 months£        
  Outpatient visits 0.29 (1.18) 0.82 (1.82) 0.13 (0.86) <0.001
  A & E visits 0.27 (1.13) 0.72 (1.68) 0.14 (0.87) <0.001
  Hospital admissions 0.24 (1.02) 0.62 (1.41) 0.13 (0.85) <0.001
Values are numbers with percentages in parenthesis, unless otherwise stated.
*p between COPD and non-COPD subjects
** MRC= Medical Research Council
€ NYHA= New York Heart Association
¥ SGRQ= St George’s Respiratory Questionnaire (data only collected in 56 COPD
and 86 non-COPD subjects)
£ expressed in mean (SD) of unscheduled events not confined to cardiac causes alone.
Table 3: Profile of respiratory symptoms, dyspnoae scores, quality-of-life status and healthcare utilisation among COPD and non-COPD subjects.