Variable PHT
Yes
PHT
No
P value
Prematurity
Yes
No

7
37

0
15

 

0.09

Cardiac defect
Yes
No

37
7

9
6

 

0.05

OSA
Yes
No

19
25

9
6

0.2
Hypothyroidism
Yes
No

18
26

5
10

0.6
Neurological disease
Yes
No

13
31

7
8

0.2
Asthma
Yes
No

42
2

15
0

0.4
Chest Infection
Yes
No

37
7

8
7

0.01
GER
Yes
No

22
22

4
11

0.1
PHT- Pulmonary hypertension
OSA- Obstructive sleep apnea
Table 2: Factors affect (PHT) development in patients with Down syndrome.