Variables

Baseline

4 months

12 months

ASD

VSD

P value

ASD

VSD

P value

ASD

VSD

P value

LVEDV index

55.5±12.2

67.3±27.6

0.413

56.52±15.78

76.22±32.01

0.263

56.37±12.17

72.65±30.00

0.30

LV mass index (g/m2)

44.9±10.2

47.8±23

0.763

41.78±6.65

49.61±18.76

0.407

39.98±6.75

52.22±18.13

0.2

LVESV index

20.7±6.3

34.9±4.6

0.348

21.44±10.17

34.52±25.31

0.321

18.65±7.34

3.00±21.8

0.22

LVSV index

37.7±6.3

34.8±4.6

0.348

35.09±7.63

41.616.94

0.227

37.0±6.94

40.23±8.51

0.549

LVEF (%)

64.4±15.2

56.3±15.3

0.453

63.9±11.39

59.32±14.97

0.617

67.42±7.44

59.27±12.74

0.26

RVEDV index

143.2±60

74.6±26.0

0.073

144.37±63.41

71.65±27.56

0.072

144.31±58.69

73.12±37.71

0.075

RV mass index (g/m2)

1.2±0.4

1.0±0.4

0.426

1.25±0.34

0.86±0.35

0.14

50.43±14.07

46.71±21.48

0.76

RVESV index

92.2±51.7

36.3±22.6

0.086

91.8±53.81

33..64±22.11

0.085

90.39±48.87

33.00±23.32

0.07

RVSV index

50.9±11.8

38.2±4.5

0.087

52.57±14.38

38.0±6.95

0.108

53.92±15.35

40.09±14.52

0.26

RVEF (%)

38.3±11.5

54.6±14.5

0.101

38.72±10.55

56.27±13.79

0.066

39.24±10.80

57.53±7.66

0.025*

Total myocardial scar (mm2)

1,275.4±522.8

1,435.6±894.9

0.738

1,327.86±606.69

1,159.58±696.13

0.811

1,277.54±605.31

1,181.86±741.38

0.83

% scar index (%/m2)

5.6±3.2

5.9±1.9

0.87

5.77±3.13

5.09±1.93

0.693

920.27±488.13

1181.86±741.38

0.97

LVEDV: left ventricular end diastolic volume, LV: left ventricle, LVESV: left ventricular end systolic volume, LVSV: left ventricular stroke volume, LVEF: left ventricular ejection fraction, RVEDV: right ventricular end diastolic volume, RV: right ventricle, RVESV: right ventricular end systolic volume, RVSV: right ventricular stroke volume,
RVEF: right ventricular ejection fraction
Table 4: demonstrated CMR data when compared in subgroup at baseline, 4 month and 12 month of treatment (P value <0.05 *signifies statistical significance).