Number (%)   Restriction** Total
No Yes
Obstruction* No 52 (34) 60 (39) 112 (73)
Yes 30 (19) 12 (8) 42 (27)
Total 82 (53) 72 (47) 154 (100)
* Obstruction was defined as FEV1/FVC less than 70%
** Restriction was defined as FVC less than 80% predicted for age and height
Table 3: The distribution of obstructive and restrictive ventilatory defects in 154 patients with sickle cell disease. The number of sickle cell disease patients (percentage of total) is shown.