Group A n = 1403 Group B n = 114 p - value
Overall, n (%) 206 (14.7) 114 (100) 0.001
ineffectiveness 130 (9.3) 103 (90.3) 0.036
sequential therapy 15 (1.1) 7 (6.7) 0.04
deescalation 42 (3.0) 0.0 0.001
intolerance 19 (1.5) 2(1.5) 1
resistance 0.0 2(1.4) 0.001
Table 4: Change of antibiotic therapy