| Clinical sign |
Clonidine group (n=120) |
Dextromethorphan group (n=120) |
Placebo
group (n=120) |
P-value |
| Heart rate (/min) |
|
|
|
|
| Before injection |
79.08 ± 12.90 |
87.82 ± 19.29 |
88.56 ± 16.74 |
< 0.001 |
| After injection |
80.65 ± 15.33 |
87.97 ± 15.49 |
90.27 ± 16.10 |
< 0.001 |
| Systolic blood pressure (mmHg) |
|
|
|
|
| Before injection |
124.05 ± 15.89 |
132.05 ± 17.05 |
132.52 ± 17.28 |
< 0.001 |
| After injection |
122.63 ± 15.78 |
127.87 ± 16.61 |
128.14 ± 16.33 |
0.013 |
| Diastolic blood pressure (mmHg) |
|
|
|
|
| Before injection |
76.22 ± 10.37 |
81.73 ± 11.40 |
83.16 ± 11.60 |
< 0.001 |
| After injection |
75.55 ± 11.68 |
78.82 ± 10.83 |
80.03 ± 12.12 |
0.009 |
| Mean arterial pressure (mmHg) |
|
|
|
|
| Before injection |
91.73 ± 12.13 |
99.18 ± 12.57 |
98.65 ± 13.04 |
< 0.001 |
| After injection |
91.27 ± 13.17 |
94.72 ± 12.63 |
95.24 ± 12.85 |
0.036 |
Data are presented as mean ± SD |
