Mild N=32 Moderate N=27 Severe N=23 V. Severe N=19 Urine Desmosine (ng/mg creatinine) 12.282.67 14.591.76 17.52 1.65* 20.111.45** Blood Desmosine(ng/ml) 0.270.021 0.300.014 0.310.013* 0.36**

Table 3: Desmosine mean levels in relation to severity of COPD.