Figure 2: Leukocyte-mediated ECM degradation in response to LPS+FMLP or HKS. Leukocytes isolated from the species identified were stimulated using either a combination of LPS + FMLP (black bars) or heat-killed Staphylococcus aureus (HKS, grey bars). White bars represent the amount of matrix degradation observed after 6 hours in the absence of any added stimuli. Matrix degradation is represented as the percentage of radioactivity recovered in the supernatant relative to the total amount of radioactivity recovered after complete matrix solubalization with 2 M NaOH. Each value is the mean ± SEM of 6 or more measurements.