Figure 4: Inhibition of LPS-elicited neutrophilia and changes in plasma insulin and blood glucose following treatment with Compounds 1, 2 and 3 Rats were pre-dosed with compound orally 1 hour prior to lung LPS challenge. Five hours post-challenge, blood samples were collected and the lungs lavaged. The inhibition of LPS-elicited neutrophilia, combined with plasma levels of insulin and blood levels of glucose are plotted against serum concentrations of (a) compound 1, (b) compound 2, and (c) compound 3. Each point in the geometric mean ± SEM of 6 animals.