Table 1

Compound	Gamma IC₅₀, nM^a	Alpha IC₅₀, nM^a	Beta IC₅₀, nM^a	Delta IC₅₀, nM^a
1	185 (120-287)	277 (192-400)	923 (612-1390)	1210 (735-1990)
2	69 (46-104)	389 (265-571)	742 (489-1130)	927 (693-1240)
3	114 (91-142)	678 (475-467)	2950 (2310-3780)	1930 (1460-2550)

^aValues are geomeans of at least 8 experiments, 95% confidence limits are given in parentheses.

Table 1: Human PI3K enzyme isoform inhibition by compounds 1, 2 and 3.