IL-8-stimulated neutrophil shape change
Compound
Human lysed blood IC
50
, nM
a
Rat whole blood IC
50
, nM
a
1
67(n=2)
740(n=5)
2
166(n=2)
826(n=3)
3
139(n=2)
582(n=2)
Table 2:
Human and rat IL-8 stimulated neutrophil shape-change inhibition by compounds 1, 2, and 3.
