Parameter
N
H
N+Cur
H+Cur
ROS nmol/min/mg/tissue
72.5 ± 12
198 ± 6a
76.2 ± 13
81.6 ± 12b
MDA nmol/gm/tissue
10.52 ± 2
50.63 ± 2a
10.23 ± 2
9.28 ± 1.3b
GSH μmol/gm tissue
4.2 ± 0.6
2.8 ± 0.4a
3.5 ± 0.84
3.94 ± 0.34b
GPx U/mg protein
0.132 ± 0.03
0.86 ± 0.1a
0.138 ± 0.06
0.140 ± 0.05b
SOD U/mg protein
0.51 ± 0.09
0.35 ± 0.07a
0.57 ± 0.1
0.54 ± 0.1b
Table 1:
Effect of curcumin on lung Reactive Oxygen Species (ROS) generation, lipid peroxidation (MDA) and antioxidant status (GSH, GPx, and SOD) in lungs of rats exposed to hypoxia at 7620 m for 6 h.