Measurements Method
Physical examination   By trained nurses
Age, gender, height, weight,    
Clinical history   Using a uniform questionnaire
Habitat area    
Environmental exposure Cooking and heating fuels  
Cigarette smoking Current/ ex-/ never, (pack years)  
Quality of life CAT  
Respiratory symptoms Cough, sputum, dyspnea†, wheezing  
Medical illness    
Pulmonary function test (pre- and post-spirometry)   As per ATS/ERS task force recommendations
FEV1/FVC Ratio  
FEV1 Liter, % of predicted  
FVC Liter, % of predicted  
Chest CT scan Inspiratory V950 (%) Wall area (%) Mean lung density ratio  
Laboratory test CBC, chemistry, electrolyte, CRP  
Blood, urine sample   Storage‡
Every 3 months    
Clinical history   Telephone interviews
Every years    
Clinical history    
Pulmonary function test    
Every 3 years    
Clinical history Clinical history Clinical history
Pulmonary function test Pulmonary function test Pulmonary function test
Chest CT scan    
†Dyspnea is graded with modified Medical Research Council dyspnea scale.
‡Blood and urine sample will be in storage for future genetic study and we have plan to measure the level of heavy metal poisoning (lead, mercury, cadmium).
CAT=COPD assessment test, ATS=American Thoracic Society, ERS=European Respiratory Society
FEV1=forced expiratory volume in 1 second, FVC=forced vital capacity,
V950=volume fraction of the lung below -950 HU, Wall area (%)=wall area/(wall area + lumen area)×100
Mean lung density ratio=mean lung density ratio of full expiration and inspiration
CBC=complete blood count, CRP=C-reactive protein.
Table 1: Summary of clinical measures collected in the chronic obstructive lung disease in dusty area cohort.