Parasite serology negative (n= 136) Parasite serology positive (n= 14) p value
Male, n (%) 94 (69) 11 (79) 0.46
Age (years)* 69 (0.8) 64.5 (3) 0.24
Body mass index (kg/m2) 26 (0.4) 27 (1.7) 0.73
Pack years smoked 46 (30-60) 39 (28-79) 0.89
Exacerbations in last year 3 (1-5) 2 (0-7.5) 0.68
ICS (BDP equivalent) (mcg/day) 2000 (900-2000) 2000 (800-2000) 0.86
FEV1% predicted, (%) 49 (1.7) 45.7 (4.8) 0.69
 FEV1/FVC (%) * 49 (1.1) 50 (3.2) 0.80
Reversibility, % 3.7(-1.3- 10) 0.69(-6.2- 6.7) 0.10
Sputum TCCx106/g 3.6 (1.5-7.9) 1.8 (0.75-4.5) 0.06
Sputum neutrophils (%) 73 (53-89) 60 (37-77) 0.11
Sputum eosinophils (%) 1.0 (0.25-3) 0.75 (0.44-2.1) 0.89
AUC sputum eosinophils %/year 0.79 (0.27-1.1) 0.41 (0.25-2.2) 0.30
PB. eosinophils (x109/L) 0.22 (0.13 - 0.34) 0.17 (0.09 - 0.29) 0.22
MRC Dyspnoea Scale 3 (2-4) 3 (2-3) 0.44
SGRQ Total Score* 51 (1.6) 56 (4.4) 0.34
CRQ total score* 16 (0.41) 17 (0.95) 0.47
VAS Cough (mm) 33 (13-54) 30 (13-72) 0.93
VAS Dyspnoea (mm) 46 (23-67) 50 (24-69) 0.79
VAS Sputum Production (mm) 31 (11-55) 37 (6-55) 0.96
VAS Sputum Purulence (mm) 21 (8-49) 26 (10-51) 0.82
Table 1: Baseline Characteristics of parasite serology positive versus negative COPD subjects